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mmors Long-term use at high doses may cause_ • Flaky, dry, and yellowish discoloration of'hesiin • Hair loss(alopecia) • Par.ial loss of hewing • Loss of appetito Like alcohol, kava may havemtoxciting effects and should not be taken before opening a car or ocher machinery. Possib a Interactions DO NOl take kava umessyou are under the supervis on of a doctor, espedally if you are being treated far disease. DO NOI take sava wit-. presripnon or over -rhe -counter medications. Kava may interact with the following. Anticonvulsants. Kava may increase he effects o` medications, such as phonytom (Dilantin). that arc used to treat spheric . Alcohol. DO N01 use kava and alcohol mgether. Tee, risk of impairment and the irk of`fiver damage a -e greatly increased_ Anti -anxiety agents. Kava may ircrcase the effects of CNS depressants salt a, heazodiazepmes, used for ;ic m distarbanc es or anxiety (oar icularly alprazolam o - Xanax, and barbiturates (such as pentobarbital), which are used 'or sle: a d sordcrs and ,(,iiures. Benzodiazep nes nclude • Alprazolam (Xanax) • Diazepam (Vanufit • Lorazewu,(At v ani • Triazolam ,Halcir;) • C h lord i azepnxi He (I ionarn) Diuretics (water pills). These drugs help r d the body P- excess flu d Kava can make the o"ects o, These drugs stronger, raising The risk of dehydratlon Phenothiazine medications. Kava rtav i crease the r sk o ride effects assooaled with an,nothiazne medications ;of.cr used to, too treatment of ; chlzoichrenia), induding chlorp,omaz ne ; fhorazin,j, ane p,omethazlne (Phenergan), we ch is used as an intit- lstamme Levodopa. here ^.a% been al '.Pas- one repot rhar kava may reduce the effectiveness o` levodopa, a medication used to trey arkinrn n4 disease. Vor. shmild not take kava ifyoa are rdung any medicaticns containing'evodop or f van have Parkinson's disease.