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10120/22, 1142 AM Kratom Unsafeavd, eratI u-+h-ynQruc In addition, substances that are made from kratom may be contaminated with salmonella bacteria. As of April 2018, more than 130 people in 38 states became ill with Salmonella after taking kratom. Salmonella poisoning may be fatal, and the U.S. Food and Drug Administration has linked more than 35 deaths to Salmonella -tainted kratom. Salmonella contamination has no obvious signs, so the best way to avoid becoming ill is to avoid products that may contain it. Kratom is not currently regulated in the United Stales, and federal agencies are taking action to combat false claims about kratom. In the meantime, your safest option is to work with your doctor to find other treatment options. Show References 1. Chien GCC, etal. Is kratom the new 'legal high' on the block 4: The case of an emerging ap oid -eceper agonist with substance abuse potential. Pain Physician. 2017:20: E195. 2. Feng L. at al. New psychoactive substances of natural origin A brief review. Journal of Food and Drug Analysis. 2017:25'461. 3. Griffin III OI I, of at Do you get what you paid for? An examination of products advertised as kratom. Journal of Psychoactive Drugs. 2016:48:330. 4. Drug Enforcement Administration. Kratom fMltragyna spec red Korth) hops -Ilwww_add divers ion, used gov/drug chem m'c/kratom. put Accessed April 17, 2018, 5. Yusaff NHM, at al. Opioid receptors mediate the acquisition_ bat not the exp-ession of mitragynlne-induced conditioned place preference In rats. Behavioural Brair Research. 2017,332'.1_ 6. Died J, or al. Kratom, an emerging drug of abase A case report of overdose and management of withdrawal. \. Anesthesia 8 Analgesia Case Reports In press. Accessed May 2. 7018. 7. Swagger MT, et al. Experfeoces of K -atom users A quatauve, analys s. Journal of Psychoactive Drugs. 2015,47:360. 8. Fox J, at al. Drugs of abuse and novel psychoactive substances at outdoor music festivals In Colorado. Substance Use & Misuse. In press. Accessed May 2, 2015. 9. Kowalczuk AP, at al. Comprehensive methodology for ,densification of kratom in police laboratories. Forens c Science Internaional. 2013 233238. 10. Fluyua D, at al Biochemical berefic d agncso and discal risks of kratom. Frontiers in Psychiatry. 2017,8:62. 't. Castillo A, at al _ Postero- reversible Ieukoenceph rlopathy sycdrome affer kratom ingestion. Baylor University Medical Center Proceedings. 2017.30: 355. 12. Gr,minnt n O. Patterns of kratom use and roalth I^pact In the US — If eselfs from an on ine survey. D, ug ane Alcohol Dependence. 2017, 176 63. 13. Drago JD, or al. The Farm In kratom. The Oncologist 2017:22.1010. 14. Pizarro-Osilla C. Introducing.. kratom. In press. Accessed May 2, 2018. 5. Kruegel AC. of al. The medloical cnerrlstry and neuropharmacology of kratom: A nrelimmary discussion of a promising medianal plant and analysis of ds potential for abuse. Neuropharmacology. In press. Accessed May 2.2n18. 16. Ismail I, at al_ Kratom and future oeatment for the opioid add,ctlon and chronic palm. Pericula benehcium? Current Drug Targets- If press. Accessec May 2, 2018 [tlps/r M"od""o" IVr r11,1�10 Omer Patty^ I krelo, on CNP'"'➢ 3o